Modeling Early Radiation DNA Damage Occurring During (177)Lu-DOTATATE Radionuclide Therapy

The aim of this study was to build a simulation framework to evaluate the number of DNA double-strand breaks (DSBs) induced by in vitro targeted radionuclide therapy (TRT). This work represents the first step toward exploring underlying biologic mechanisms and the influence of physical and chemical...

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Detalles Bibliográficos
Autores principales: Tamborino, Giulia, Perrot, Yann, De Saint-Hubert, Marijke, Struelens, Lara, Nonnekens, Julie, Jong, Marion De, Konijnenberg, Mark W., Villagrasa, Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society of Nuclear Medicine 2022
Materias:
Translational
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9051596/
https://www.ncbi.nlm.nih.gov/pubmed/34503959
http://dx.doi.org/10.2967/jnumed.121.262610

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9051596/
https://www.ncbi.nlm.nih.gov/pubmed/34503959
http://dx.doi.org/10.2967/jnumed.121.262610

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