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CD8-Targeted PET Imaging of Tumor-Infiltrating T Cells in Patients with Cancer: A Phase I First-in-Humans Study of (89)Zr-Df-IAB22M2C, a Radiolabeled Anti-CD8 Minibody

There is a need for in vivo diagnostic imaging probes that can noninvasively measure tumor-infiltrating CD8+ leukocytes. Such imaging probes could be used to predict early response to cancer immunotherapy, help select effective single or combination immunotherapies, and facilitate the development of...

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Detalles Bibliográficos
Autores principales:	Farwell, Michael D., Gamache, Raymond F., Babazada, Hasan, Hellmann, Matthew D., Harding, James J., Korn, Ron, Mascioni, Alessandro, Le, William, Wilson, Ian, Gordon, Michael S., Wu, Anna M., Ulaner, Gary A., Wolchok, Jedd D., Postow, Michael A., Pandit-Taskar, Neeta
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Society of Nuclear Medicine 2022
Materias:	Clinical (Oncology: Other)
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9051598/ https://www.ncbi.nlm.nih.gov/pubmed/34413145 http://dx.doi.org/10.2967/jnumed.121.262485

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