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Histone H3K4me3 breadth in hypoxia reveals endometrial core functions and stress adaptation linked to endometriosis

Trimethylation of histone H3 at lysine 4 (H3K4me3) is a marker of active promoters. Broad H3K4me3 promoter domains have been associated with cell type identity, but H3K4me3 dynamics upon cellular stress have not been well characterized. We assessed this by exposing endometrial stromal cells to hypox...

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Detalles Bibliográficos
Autores principales: Rytkönen, Kalle T., Faux, Thomas, Mahmoudian, Mehrad, Heinosalo, Taija, Nnamani, Mauris C., Perheentupa, Antti, Poutanen, Matti, Elo, Laura L., Wagner, Günter P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9051620/
https://www.ncbi.nlm.nih.gov/pubmed/35494227
http://dx.doi.org/10.1016/j.isci.2022.104235