Novel synthesis of divergent aryl imidazoles from ketones involving copper-catalyzed α-amination and oxidative C–C bond cleavage

A one-pot synthesis, initiated by a copper salt with inorganic (NH(4))(2)CO(3) as the nitrogen source, forms divergent aryl imidazole derivatives from ketones via α-amination and oxidative C–C bond cleavage reactions. The approach provides a simple and rapid synthesis of imidazole derivatives and ha...

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Detalles Bibliográficos
Autores principales: Huang, Jiangkun, Luo, Lan, Xing, Naiguo, Gu, Linghui, Li, Chen, Han, Qiao, Zheng, Shilong, He, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9051655/
https://www.ncbi.nlm.nih.gov/pubmed/35492973
http://dx.doi.org/10.1039/d0ra01408g
Descripción
Sumario:A one-pot synthesis, initiated by a copper salt with inorganic (NH(4))(2)CO(3) as the nitrogen source, forms divergent aryl imidazole derivatives from ketones via α-amination and oxidative C–C bond cleavage reactions. The approach provides a simple and rapid synthesis of imidazole derivatives and has certain versatility.

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