Novel synthesis of divergent aryl imidazoles from ketones involving copper-catalyzed α-amination and oxidative C–C bond cleavage

A one-pot synthesis, initiated by a copper salt with inorganic (NH(4))(2)CO(3) as the nitrogen source, forms divergent aryl imidazole derivatives from ketones via α-amination and oxidative C–C bond cleavage reactions. The approach provides a simple and rapid synthesis of imidazole derivatives and ha...

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Detalles Bibliográficos
Autores principales: Huang, Jiangkun, Luo, Lan, Xing, Naiguo, Gu, Linghui, Li, Chen, Han, Qiao, Zheng, Shilong, He, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9051655/
https://www.ncbi.nlm.nih.gov/pubmed/35492973
http://dx.doi.org/10.1039/d0ra01408g
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author Huang, Jiangkun
Luo, Lan
Xing, Naiguo
Gu, Linghui
Li, Chen
Han, Qiao
Zheng, Shilong
He, Ling
author_facet Huang, Jiangkun
Luo, Lan
Xing, Naiguo
Gu, Linghui
Li, Chen
Han, Qiao
Zheng, Shilong
He, Ling
author_sort Huang, Jiangkun
collection PubMed
description A one-pot synthesis, initiated by a copper salt with inorganic (NH(4))(2)CO(3) as the nitrogen source, forms divergent aryl imidazole derivatives from ketones via α-amination and oxidative C–C bond cleavage reactions. The approach provides a simple and rapid synthesis of imidazole derivatives and has certain versatility.
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spelling pubmed-90516552022-04-29 Novel synthesis of divergent aryl imidazoles from ketones involving copper-catalyzed α-amination and oxidative C–C bond cleavage Huang, Jiangkun Luo, Lan Xing, Naiguo Gu, Linghui Li, Chen Han, Qiao Zheng, Shilong He, Ling RSC Adv Chemistry A one-pot synthesis, initiated by a copper salt with inorganic (NH(4))(2)CO(3) as the nitrogen source, forms divergent aryl imidazole derivatives from ketones via α-amination and oxidative C–C bond cleavage reactions. The approach provides a simple and rapid synthesis of imidazole derivatives and has certain versatility. The Royal Society of Chemistry 2020-04-06 /pmc/articles/PMC9051655/ /pubmed/35492973 http://dx.doi.org/10.1039/d0ra01408g Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/
spellingShingle Chemistry
Huang, Jiangkun
Luo, Lan
Xing, Naiguo
Gu, Linghui
Li, Chen
Han, Qiao
Zheng, Shilong
He, Ling
Novel synthesis of divergent aryl imidazoles from ketones involving copper-catalyzed α-amination and oxidative C–C bond cleavage
title Novel synthesis of divergent aryl imidazoles from ketones involving copper-catalyzed α-amination and oxidative C–C bond cleavage
title_full Novel synthesis of divergent aryl imidazoles from ketones involving copper-catalyzed α-amination and oxidative C–C bond cleavage
title_fullStr Novel synthesis of divergent aryl imidazoles from ketones involving copper-catalyzed α-amination and oxidative C–C bond cleavage
title_full_unstemmed Novel synthesis of divergent aryl imidazoles from ketones involving copper-catalyzed α-amination and oxidative C–C bond cleavage
title_short Novel synthesis of divergent aryl imidazoles from ketones involving copper-catalyzed α-amination and oxidative C–C bond cleavage
title_sort novel synthesis of divergent aryl imidazoles from ketones involving copper-catalyzed α-amination and oxidative c–c bond cleavage
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9051655/
https://www.ncbi.nlm.nih.gov/pubmed/35492973
http://dx.doi.org/10.1039/d0ra01408g
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