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A rare case of disseminated superficial porokeratosis-Case report

Porokeratosis is a keratinization disorder characterized by hyperkeratotic sharply demarcated plaques with central atrophy and histopathologically, by cornoid lamella. A 30-year-old male presented with multiple pruritic dark raised skin lesions over the trunk, face, and upper limbs for past 3 years....

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Autores principales: Ramakrishnan, Ramachandran, Vignesh, T. Arun, Durai, Priya Cinna T., Narasimhan, Murali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9051733/
https://www.ncbi.nlm.nih.gov/pubmed/35495808
http://dx.doi.org/10.4103/jfmpc.jfmpc_1232_21
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author Ramakrishnan, Ramachandran
Vignesh, T. Arun
Durai, Priya Cinna T.
Narasimhan, Murali
author_facet Ramakrishnan, Ramachandran
Vignesh, T. Arun
Durai, Priya Cinna T.
Narasimhan, Murali
author_sort Ramakrishnan, Ramachandran
collection PubMed
description Porokeratosis is a keratinization disorder characterized by hyperkeratotic sharply demarcated plaques with central atrophy and histopathologically, by cornoid lamella. A 30-year-old male presented with multiple pruritic dark raised skin lesions over the trunk, face, and upper limbs for past 3 years. Cutaneous examination revealed hyperkeratotic annular plaques with raised margins over face, trunk, and arms. Histopathology revealed marked hyperkeratosis with irregular acanthosis and papillomatosis. Vertical parakeratotic foci and focal hypergranulosis were seen. Hence, a diagnosis of disseminated superficial porokeratosis was made. We present this rare case which may have association with systemic disease, immunosuppression, and malignant transformation.
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spelling pubmed-90517332022-04-30 A rare case of disseminated superficial porokeratosis-Case report Ramakrishnan, Ramachandran Vignesh, T. Arun Durai, Priya Cinna T. Narasimhan, Murali J Family Med Prim Care Case Report Porokeratosis is a keratinization disorder characterized by hyperkeratotic sharply demarcated plaques with central atrophy and histopathologically, by cornoid lamella. A 30-year-old male presented with multiple pruritic dark raised skin lesions over the trunk, face, and upper limbs for past 3 years. Cutaneous examination revealed hyperkeratotic annular plaques with raised margins over face, trunk, and arms. Histopathology revealed marked hyperkeratosis with irregular acanthosis and papillomatosis. Vertical parakeratotic foci and focal hypergranulosis were seen. Hence, a diagnosis of disseminated superficial porokeratosis was made. We present this rare case which may have association with systemic disease, immunosuppression, and malignant transformation. Wolters Kluwer - Medknow 2022-03 2022-03-10 /pmc/articles/PMC9051733/ /pubmed/35495808 http://dx.doi.org/10.4103/jfmpc.jfmpc_1232_21 Text en Copyright: © 2022 Journal of Family Medicine and Primary Care https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Case Report
Ramakrishnan, Ramachandran
Vignesh, T. Arun
Durai, Priya Cinna T.
Narasimhan, Murali
A rare case of disseminated superficial porokeratosis-Case report
title A rare case of disseminated superficial porokeratosis-Case report
title_full A rare case of disseminated superficial porokeratosis-Case report
title_fullStr A rare case of disseminated superficial porokeratosis-Case report
title_full_unstemmed A rare case of disseminated superficial porokeratosis-Case report
title_short A rare case of disseminated superficial porokeratosis-Case report
title_sort rare case of disseminated superficial porokeratosis-case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9051733/
https://www.ncbi.nlm.nih.gov/pubmed/35495808
http://dx.doi.org/10.4103/jfmpc.jfmpc_1232_21
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