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N-Amino peptide scanning reveals inhibitors of Aβ(42) aggregation
The aggregation of amyloids into toxic oligomers is believed to be a key pathogenic event in the onset of Alzheimer's disease. Peptidomimetic modulators capable of destabilizing the propagation of an extended network of β-sheet fibrils represent a potential intervention strategy. Modifications...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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The Royal Society of Chemistry
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9051937/ https://www.ncbi.nlm.nih.gov/pubmed/35498502 http://dx.doi.org/10.1039/d0ra02009e |