Identification of benzothiazones containing a hexahydropyrrolo[3,4-c]pyrrol moiety as antitubercular agents against MDR-MTB

IMB1603, a spiro-benzothiazone compound discovered by our lab, displayed potent anti-MTB activity in vitro and in vivo. In this study, we reported a series of new BTZs containing the hexahydropyrrolo[3,4-c]pyrrol moiety based on the structure of IMB1603. Among them, BTZs 11 and 24 displayed potent a...

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Detalles Bibliográficos
Autores principales: Ma, Xican, Han, Bing, Wang, Aoyu, Yang, Lu, Huang, Menghao, Chowdhury, Kushan, Gu, Jian, Zhang, Kai, Lv, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9051945/
https://www.ncbi.nlm.nih.gov/pubmed/35498504
http://dx.doi.org/10.1039/d0ra00750a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9051945/
https://www.ncbi.nlm.nih.gov/pubmed/35498504
http://dx.doi.org/10.1039/d0ra00750a

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