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CRISPR-Cas knockout of miR21 reduces glioma growth

Non-coding RNAs, including microRNAs (miRNAs), support the progression of glioma. miR-21 is a small, non-coding transcript involved in regulating gene expression in multiple cellular pathways, including the regulation of proliferation. High expression of miR-21 has been shown to be a major driver of...

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Detalles Bibliográficos
Autores principales: Nieland, Lisa, van Solinge, Thomas S., Cheah, Pike See, Morsett, Liza M., El Khoury, Joseph, Rissman, Joseph I., Kleinstiver, Benjamin P., Broekman, Marike L.D., Breakefield, Xandra O., Abels, Erik R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9052041/
https://www.ncbi.nlm.nih.gov/pubmed/35572197
http://dx.doi.org/10.1016/j.omto.2022.04.001