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An approach to new chiral bicyclic imines and amines via Horner–Wadsworth–Emmons reaction

New chiral bicyclic imines, enamines and amines were prepared via Horner–Wadsworth–Emmons reaction of hexahydroquinoxalin-2(1H)-one-derived phosphonate, as the source of a phosphonate carbanion, and a wide range of structurally diverse carbonyl substrates. The simplicity of the synthetic protocol, h...

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Detalles Bibliográficos
Autores principales: Iwanejko, Jakub, Sowiński, Mateusz, Wojaczyńska, Elżbieta, Olszewski, Tomasz K., Górecki, Marcin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9052066/
https://www.ncbi.nlm.nih.gov/pubmed/35497115
http://dx.doi.org/10.1039/d0ra02646h