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GOECP/SEOR radiotheraphy guidelines for non-small-cell lung cancer
Non-small cell lung cancer (NSCLC) is a heterogeneous disease accounting for approximately 85% of all lung cancers. Only 17% of patients are diagnosed at an early stage. Treatment is multidisciplinary and radiotherapy plays a key role in all stages of the disease. More than 50% of patients with NSCL...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Baishideng Publishing Group Inc
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9052073/ https://www.ncbi.nlm.nih.gov/pubmed/35582651 http://dx.doi.org/10.5306/wjco.v13.i4.237 |
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author | Rodríguez De Dios, Núria Navarro-Martin, Arturo Cigarral, Cristina Chicas-Sett, Rodolfo García, Rafael Garcia, Virginia Gonzalez, Jose Antonio Gonzalo, Susana Murcia-Mejía, Mauricio Robaina, Rogelio Sotoca, Amalia Vallejo, Carmen Valtueña, German Couñago, Felipe |
author_facet | Rodríguez De Dios, Núria Navarro-Martin, Arturo Cigarral, Cristina Chicas-Sett, Rodolfo García, Rafael Garcia, Virginia Gonzalez, Jose Antonio Gonzalo, Susana Murcia-Mejía, Mauricio Robaina, Rogelio Sotoca, Amalia Vallejo, Carmen Valtueña, German Couñago, Felipe |
author_sort | Rodríguez De Dios, Núria |
collection | PubMed |
description | Non-small cell lung cancer (NSCLC) is a heterogeneous disease accounting for approximately 85% of all lung cancers. Only 17% of patients are diagnosed at an early stage. Treatment is multidisciplinary and radiotherapy plays a key role in all stages of the disease. More than 50% of patients with NSCLC are treated with radiotherapy (curative-intent or palliative). Technological advances-including highly conformal radiotherapy techniques, new immobilization and respiratory control systems, and precision image verification systems-allow clinicians to individualize treatment to maximize tumor control while minimizing treatment-related toxicity. Novel therapeutic regimens such as moderate hypofractionation and advanced techniques such as stereotactic body radiotherapy (SBRT) have reduced the number of radiotherapy sessions. The integration of SBRT into routine clinical practice has radically altered treatment of early-stage disease. SBRT also plays an increasingly important role in oligometastatic disease. The aim of the present guidelines is to review the role of radiotherapy in the treatment of localized, locally-advanced, and metastatic NSCLC. We review the main radiotherapy techniques and clarify the role of radiotherapy in routine clinical practice. These guidelines are based on the best available evidence. The level and grade of evidence supporting each recommendation is provided. |
format | Online Article Text |
id | pubmed-9052073 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Baishideng Publishing Group Inc |
record_format | MEDLINE/PubMed |
spelling | pubmed-90520732022-05-16 GOECP/SEOR radiotheraphy guidelines for non-small-cell lung cancer Rodríguez De Dios, Núria Navarro-Martin, Arturo Cigarral, Cristina Chicas-Sett, Rodolfo García, Rafael Garcia, Virginia Gonzalez, Jose Antonio Gonzalo, Susana Murcia-Mejía, Mauricio Robaina, Rogelio Sotoca, Amalia Vallejo, Carmen Valtueña, German Couñago, Felipe World J Clin Oncol Guidelines Non-small cell lung cancer (NSCLC) is a heterogeneous disease accounting for approximately 85% of all lung cancers. Only 17% of patients are diagnosed at an early stage. Treatment is multidisciplinary and radiotherapy plays a key role in all stages of the disease. More than 50% of patients with NSCLC are treated with radiotherapy (curative-intent or palliative). Technological advances-including highly conformal radiotherapy techniques, new immobilization and respiratory control systems, and precision image verification systems-allow clinicians to individualize treatment to maximize tumor control while minimizing treatment-related toxicity. Novel therapeutic regimens such as moderate hypofractionation and advanced techniques such as stereotactic body radiotherapy (SBRT) have reduced the number of radiotherapy sessions. The integration of SBRT into routine clinical practice has radically altered treatment of early-stage disease. SBRT also plays an increasingly important role in oligometastatic disease. The aim of the present guidelines is to review the role of radiotherapy in the treatment of localized, locally-advanced, and metastatic NSCLC. We review the main radiotherapy techniques and clarify the role of radiotherapy in routine clinical practice. These guidelines are based on the best available evidence. The level and grade of evidence supporting each recommendation is provided. Baishideng Publishing Group Inc 2022-04-24 2022-04-24 /pmc/articles/PMC9052073/ /pubmed/35582651 http://dx.doi.org/10.5306/wjco.v13.i4.237 Text en ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. https://creativecommons.org/licenses/by-nc/4.0/This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
spellingShingle | Guidelines Rodríguez De Dios, Núria Navarro-Martin, Arturo Cigarral, Cristina Chicas-Sett, Rodolfo García, Rafael Garcia, Virginia Gonzalez, Jose Antonio Gonzalo, Susana Murcia-Mejía, Mauricio Robaina, Rogelio Sotoca, Amalia Vallejo, Carmen Valtueña, German Couñago, Felipe GOECP/SEOR radiotheraphy guidelines for non-small-cell lung cancer |
title | GOECP/SEOR radiotheraphy guidelines for non-small-cell lung cancer |
title_full | GOECP/SEOR radiotheraphy guidelines for non-small-cell lung cancer |
title_fullStr | GOECP/SEOR radiotheraphy guidelines for non-small-cell lung cancer |
title_full_unstemmed | GOECP/SEOR radiotheraphy guidelines for non-small-cell lung cancer |
title_short | GOECP/SEOR radiotheraphy guidelines for non-small-cell lung cancer |
title_sort | goecp/seor radiotheraphy guidelines for non-small-cell lung cancer |
topic | Guidelines |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9052073/ https://www.ncbi.nlm.nih.gov/pubmed/35582651 http://dx.doi.org/10.5306/wjco.v13.i4.237 |
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