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Human constitutive androstane receptor represses liver cancer development and hepatoma cell proliferation by inhibiting erythropoietin signaling

The constitutive androstane receptor (CAR) is a nuclear receptor that plays a crucial role in regulating xenobiotic metabolism and detoxification, energy homeostasis, and cell proliferation by modulating the transcription of numerous target genes. CAR activation has been established as the mode of a...

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Detalles Bibliográficos
Autores principales:	Li, Zhihui, Kwon, So Mee, Li, Daochuan, Li, Linhao, Peng, Xiwei, Zhang, Junran, Sueyoshi, Tatsuya, Raufman, Jean-Pierre, Negishi, Masahiko, Wang, Xin Wei, Wang, Hongbing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9052153/ https://www.ncbi.nlm.nih.gov/pubmed/35367211 http://dx.doi.org/10.1016/j.jbc.2022.101885

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