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Accessibility of ENaC extracellular domain central core residues
The epithelial Na(+) channel (ENaC)/degenerin family has a similar extracellular architecture, where specific regulatory factors interact and alter channel gating behavior. The extracellular palm domain serves as a key link to the channel pore. In this study, we used cysteine-scanning mutagenesis to...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9052164/ https://www.ncbi.nlm.nih.gov/pubmed/35339489 http://dx.doi.org/10.1016/j.jbc.2022.101860 |