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pH-responsive and folate-coated liposomes encapsulating irinotecan as an alternative to improve efficacy of colorectal cancer treatment

Irinotecan (IRN) is a semisynthetic derivative of camptothecin that acts as a topoisomerase I inhibitor. IRN is used worldwide for the treatment of several types of cancer, including colorectal cancer, however its use can lead to serious adverse effects, as diarrhea and myelosuppression. Liposomes a...

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Detalles Bibliográficos
Autores principales:	Nunes, Shirleide Santos, Miranda, Sued Eustaquio Mendes, de Oliveira Silva, Juliana, Fernandes, Renata Salgado, de Alcântara Lemos, Janaína, de Aguiar Ferreira, Carolina, Townsend, Danyelle M., Cassali, Geovanni Dantas, Oliveira, Mônica Cristina, de Barros, André Luís Branco
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9052206/ https://www.ncbi.nlm.nih.gov/pubmed/34634556 http://dx.doi.org/10.1016/j.biopha.2021.112317

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