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A double-blind, placebo-controlled, single-ascending-dose intravenous infusion study of rHIgM22 in subjects with multiple sclerosis immediately following a relapse
BACKGROUND: Recombinant human immunoglobulin M22 (rHIgM22) has promoted remyelination in animal models and was well tolerated in people with clinically stable multiple sclerosis. OBJECTIVE: Safety/tolerability of a single rHIgM22 dose was investigated following an acute relapse and to determine whet...
Autores principales: | Greenberg, Benjamin M., Bowen, James D., Alvarez, Enrique, Rodriguez, Moses, Caggiano, Anthony O., Warrington, Arthur E., Zhao, Ping, Eisen, Andrew |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9052243/ https://www.ncbi.nlm.nih.gov/pubmed/35496758 http://dx.doi.org/10.1177/20552173221091475 |
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