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Cancer-associated fibroblasts and resistance to anticancer therapies: status, mechanisms, and countermeasures
Cancer-associated fibroblasts (CAFs) are critical components of the tumor microenvironment (TME) with diverse functions such as extracellular matrix (ECM) remodeling, modulation of metabolism and angiogenesis, and crosstalk with both cancer cells and infiltrating immune cells by production of growth...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9052457/ https://www.ncbi.nlm.nih.gov/pubmed/35488263 http://dx.doi.org/10.1186/s12935-022-02599-7 |