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Mechanisms underlying the blood pressure lowering effects of dapagliflozin, exenatide, and their combination in people with type 2 diabetes: a secondary analysis of a randomized trial
BACKGROUND: Sodium-glucose cotransporter-2 inhibitors (SGLT2i) and glucagon-like peptide-1 receptor agonists (GLP-1RA) lower blood pressure (BP). When SGLT2i and GLP-1RA are combined, synergistic effects on BP have been observed. The mechanisms underlying these BP reductions are incompletely underst...
Autores principales: | van Ruiten, Charlotte C., Smits, Mark M., Kok, Megan D., Serné, Erik H., van Raalte, Daniël H., Kramer, Mark H. H., Nieuwdorp, Max, IJzerman, Richard G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9052512/ https://www.ncbi.nlm.nih.gov/pubmed/35484607 http://dx.doi.org/10.1186/s12933-022-01492-x |
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