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Fibroblast growth factor receptor 4 promotes glioblastoma progression: a central role of integrin-mediated cell invasiveness

Glioblastoma (GBM) is characterized by a particularly invasive phenotype, supported by oncogenic signals from the fibroblast growth factor (FGF)/ FGF receptor (FGFR) network. However, a possible role of FGFR4 remained elusive so far. Several transcriptomic glioma datasets were analyzed. An extended...

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Detalles Bibliográficos
Autores principales: Gabler, Lisa, Jaunecker, Carola Nadine, Katz, Sonja, van Schoonhoven, Sushilla, Englinger, Bernhard, Pirker, Christine, Mohr, Thomas, Vician, Petra, Stojanovic, Mirjana, Woitzuck, Valentin, Laemmerer, Anna, Kirchhofer, Dominik, Mayr, Lisa, LaFranca, Mery, Erhart, Friedrich, Grissenberger, Sarah, Wenninger-Weinzierl, Andrea, Sturtzel, Caterina, Kiesel, Barbara, Lang, Alexandra, Marian, Brigitte, Grasl-Kraupp, Bettina, Distel, Martin, Schüler, Julia, Gojo, Johannes, Grusch, Michael, Spiegl-Kreinecker, Sabine, Donoghue, Daniel J., Lötsch, Daniela, Berger, Walter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9052585/
https://www.ncbi.nlm.nih.gov/pubmed/35484633
http://dx.doi.org/10.1186/s40478-022-01363-2