DeepRepeat: direct quantification of short tandem repeats on signal data from nanopore sequencing

Despite recent improvements in basecalling accuracy, nanopore sequencing still has higher error rates on short-tandem repeats (STRs). Instead of using basecalled reads, we developed DeepRepeat which converts ionic current signals into red-green-blue channels, thus transforming the repeat detection p...

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Detalles Bibliográficos
Autores principales: Fang, Li, Liu, Qian, Monteys, Alex Mas, Gonzalez-Alegre, Pedro, Davidson, Beverly L., Wang, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9052667/
https://www.ncbi.nlm.nih.gov/pubmed/35484600
http://dx.doi.org/10.1186/s13059-022-02670-6

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