PPh(3)/NaI driven photocatalytic decarboxylative radical cascade alkylarylation reaction of 2-isocyanobiaryls

The first triphenylphosphine/sodium iodide driven photocatalytic decarboxylative cascade cyclization of 2-isocyano-biaryls with alkyl N-hydroxyphthalimide (NHP) esters was developed. This operationally simple protocol results in multiple carbon–carbon bond formation under transition metal free condi...

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Detalles Bibliográficos
Autores principales: Wadekar, Ketan, Aswale, Suraj, Yatham, Veera Reddy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9052874/
https://www.ncbi.nlm.nih.gov/pubmed/35498830
http://dx.doi.org/10.1039/d0ra03211e
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author Wadekar, Ketan
Aswale, Suraj
Yatham, Veera Reddy
author_facet Wadekar, Ketan
Aswale, Suraj
Yatham, Veera Reddy
author_sort Wadekar, Ketan
collection PubMed
description The first triphenylphosphine/sodium iodide driven photocatalytic decarboxylative cascade cyclization of 2-isocyano-biaryls with alkyl N-hydroxyphthalimide (NHP) esters was developed. This operationally simple protocol results in multiple carbon–carbon bond formation under transition metal free conditions, affording a novel and environmentally benign entry to producing 6-alkyl phenanthridines with moderate to good yields.
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spelling pubmed-90528742022-04-29 PPh(3)/NaI driven photocatalytic decarboxylative radical cascade alkylarylation reaction of 2-isocyanobiaryls Wadekar, Ketan Aswale, Suraj Yatham, Veera Reddy RSC Adv Chemistry The first triphenylphosphine/sodium iodide driven photocatalytic decarboxylative cascade cyclization of 2-isocyano-biaryls with alkyl N-hydroxyphthalimide (NHP) esters was developed. This operationally simple protocol results in multiple carbon–carbon bond formation under transition metal free conditions, affording a novel and environmentally benign entry to producing 6-alkyl phenanthridines with moderate to good yields. The Royal Society of Chemistry 2020-04-25 /pmc/articles/PMC9052874/ /pubmed/35498830 http://dx.doi.org/10.1039/d0ra03211e Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by/3.0/
spellingShingle Chemistry
Wadekar, Ketan
Aswale, Suraj
Yatham, Veera Reddy
PPh(3)/NaI driven photocatalytic decarboxylative radical cascade alkylarylation reaction of 2-isocyanobiaryls
title PPh(3)/NaI driven photocatalytic decarboxylative radical cascade alkylarylation reaction of 2-isocyanobiaryls
title_full PPh(3)/NaI driven photocatalytic decarboxylative radical cascade alkylarylation reaction of 2-isocyanobiaryls
title_fullStr PPh(3)/NaI driven photocatalytic decarboxylative radical cascade alkylarylation reaction of 2-isocyanobiaryls
title_full_unstemmed PPh(3)/NaI driven photocatalytic decarboxylative radical cascade alkylarylation reaction of 2-isocyanobiaryls
title_short PPh(3)/NaI driven photocatalytic decarboxylative radical cascade alkylarylation reaction of 2-isocyanobiaryls
title_sort pph(3)/nai driven photocatalytic decarboxylative radical cascade alkylarylation reaction of 2-isocyanobiaryls
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9052874/
https://www.ncbi.nlm.nih.gov/pubmed/35498830
http://dx.doi.org/10.1039/d0ra03211e
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AT yathamveerareddy pph3naidrivenphotocatalyticdecarboxylativeradicalcascadealkylarylationreactionof2isocyanobiaryls

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