Ingenuity pathway analysis of the human cardiac cell Atlas identifies differences between right and left ventricular cardiomyocytes

Pharmaceuticals for left ventricular (LV) dysfunction do not have similar success in right ventricular (RV) failure, which may reflect biological differences between the ventricles. In this study, we performed Ingenuity Pathway Analysis of the Human Cell Atlas to understand how the transcriptomic si...

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Autores principales: Prisco, Sasha Z., Kazmirczak, Felipe, Thenappan, Thenappan, Prins, Kurt W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9052994/
https://www.ncbi.nlm.nih.gov/pubmed/35506094
http://dx.doi.org/10.1002/pul2.12011
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author Prisco, Sasha Z.
Kazmirczak, Felipe
Thenappan, Thenappan
Prins, Kurt W.
author_facet Prisco, Sasha Z.
Kazmirczak, Felipe
Thenappan, Thenappan
Prins, Kurt W.
author_sort Prisco, Sasha Z.
collection PubMed
description Pharmaceuticals for left ventricular (LV) dysfunction do not have similar success in right ventricular (RV) failure, which may reflect biological differences between the ventricles. In this study, we performed Ingenuity Pathway Analysis of the Human Cell Atlas to understand how the transcriptomic signatures of the RV and LV differ.
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spelling pubmed-90529942022-05-02 Ingenuity pathway analysis of the human cardiac cell Atlas identifies differences between right and left ventricular cardiomyocytes Prisco, Sasha Z. Kazmirczak, Felipe Thenappan, Thenappan Prins, Kurt W. Pulm Circ Research Letter Pharmaceuticals for left ventricular (LV) dysfunction do not have similar success in right ventricular (RV) failure, which may reflect biological differences between the ventricles. In this study, we performed Ingenuity Pathway Analysis of the Human Cell Atlas to understand how the transcriptomic signatures of the RV and LV differ. John Wiley and Sons Inc. 2022-01-05 /pmc/articles/PMC9052994/ /pubmed/35506094 http://dx.doi.org/10.1002/pul2.12011 Text en © 2021 The Authors. Pulmonary Circulation published by Wiley Periodicals LLC on behalf of the Pulmonary Vascular Research Institute. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Research Letter
Prisco, Sasha Z.
Kazmirczak, Felipe
Thenappan, Thenappan
Prins, Kurt W.
Ingenuity pathway analysis of the human cardiac cell Atlas identifies differences between right and left ventricular cardiomyocytes
title Ingenuity pathway analysis of the human cardiac cell Atlas identifies differences between right and left ventricular cardiomyocytes
title_full Ingenuity pathway analysis of the human cardiac cell Atlas identifies differences between right and left ventricular cardiomyocytes
title_fullStr Ingenuity pathway analysis of the human cardiac cell Atlas identifies differences between right and left ventricular cardiomyocytes
title_full_unstemmed Ingenuity pathway analysis of the human cardiac cell Atlas identifies differences between right and left ventricular cardiomyocytes
title_short Ingenuity pathway analysis of the human cardiac cell Atlas identifies differences between right and left ventricular cardiomyocytes
title_sort ingenuity pathway analysis of the human cardiac cell atlas identifies differences between right and left ventricular cardiomyocytes
topic Research Letter
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9052994/
https://www.ncbi.nlm.nih.gov/pubmed/35506094
http://dx.doi.org/10.1002/pul2.12011
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