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Genetic and phenotypic analysis of the causal relationship between aging and COVID-19

BACKGROUND: Epidemiological studies revealed that the elderly and those with comorbidities are most affected by COVID-19, but it is important to investigate shared genetic mechanisms between COVID-19 risk and aging. METHODS: We conducted a multi-instrument Mendelian Randomization analysis of multipl...

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Detalles Bibliográficos
Autores principales: Ying, Kejun, Zhai, Ranran, Pyrkov, Timothy V., Shindyapina, Anastasia V., Mariotti, Marco, Fedichev, Peter O., Shen, Xia, Gladyshev, Vadim N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9053191/
https://www.ncbi.nlm.nih.gov/pubmed/35602207
http://dx.doi.org/10.1038/s43856-021-00033-z