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A case series shows independent vestibular labyrinthine function after major surgical trauma to the human cochlea

BACKGROUND: The receptors for hearing and balance are housed together in the labyrinth of the inner ear and share the same fluids. Surgical damage to either receptor system was widely believed to cause certain permanent loss of the receptor function of the other. That principle, however, has been ca...

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Autores principales: Plontke, Stefan K., Rahne, Torsten, Curthoys, Ian S., Håkansson, Bo, Fröhlich, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9053204/
https://www.ncbi.nlm.nih.gov/pubmed/35602216
http://dx.doi.org/10.1038/s43856-021-00036-w
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author Plontke, Stefan K.
Rahne, Torsten
Curthoys, Ian S.
Håkansson, Bo
Fröhlich, Laura
author_facet Plontke, Stefan K.
Rahne, Torsten
Curthoys, Ian S.
Håkansson, Bo
Fröhlich, Laura
author_sort Plontke, Stefan K.
collection PubMed
description BACKGROUND: The receptors for hearing and balance are housed together in the labyrinth of the inner ear and share the same fluids. Surgical damage to either receptor system was widely believed to cause certain permanent loss of the receptor function of the other. That principle, however, has been called into question because there have been anecdotal reports in individual patients of at least partial preservation of cochlear function after major surgical damage to the vestibular division and vice versa. METHODS: We performed specific objective vestibular function tests before and after surgical trauma (partial or subtotal cochlear removal) for treatment of intracochlear tumors in 27 consecutive patients in a tertiary referral center. Vestibular function was assessed by calorics (low-frequency response of the lateral semicircular canal), vestibulo-ocular reflex by video head impulse test (vHIT) of the three semicircular canals, cervical and ocular vestibular evoked myogenic potentials (cVEMP, saccule and oVEMP, utricle). Preoperative and postoperative distributions were compared with paired t-tests. RESULTS: Here we show that there was no significant difference between pre- and post-operative measures for all tests of the five vestibular organs, and that after major surgical cochlear trauma, the vestibular receptors continue to function independently. CONCLUSIONS: These surprising observations have important implications for our understanding of the function and the surgery of the peripheral auditory and vestibular system in general and open up new possibilities for the development, construction and evaluation of neural interfaces for electrical or optical stimulation of the peripheral auditory and vestibular nervous system.
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spelling pubmed-90532042022-05-20 A case series shows independent vestibular labyrinthine function after major surgical trauma to the human cochlea Plontke, Stefan K. Rahne, Torsten Curthoys, Ian S. Håkansson, Bo Fröhlich, Laura Commun Med (Lond) Article BACKGROUND: The receptors for hearing and balance are housed together in the labyrinth of the inner ear and share the same fluids. Surgical damage to either receptor system was widely believed to cause certain permanent loss of the receptor function of the other. That principle, however, has been called into question because there have been anecdotal reports in individual patients of at least partial preservation of cochlear function after major surgical damage to the vestibular division and vice versa. METHODS: We performed specific objective vestibular function tests before and after surgical trauma (partial or subtotal cochlear removal) for treatment of intracochlear tumors in 27 consecutive patients in a tertiary referral center. Vestibular function was assessed by calorics (low-frequency response of the lateral semicircular canal), vestibulo-ocular reflex by video head impulse test (vHIT) of the three semicircular canals, cervical and ocular vestibular evoked myogenic potentials (cVEMP, saccule and oVEMP, utricle). Preoperative and postoperative distributions were compared with paired t-tests. RESULTS: Here we show that there was no significant difference between pre- and post-operative measures for all tests of the five vestibular organs, and that after major surgical cochlear trauma, the vestibular receptors continue to function independently. CONCLUSIONS: These surprising observations have important implications for our understanding of the function and the surgery of the peripheral auditory and vestibular system in general and open up new possibilities for the development, construction and evaluation of neural interfaces for electrical or optical stimulation of the peripheral auditory and vestibular nervous system. Nature Publishing Group UK 2021-10-06 /pmc/articles/PMC9053204/ /pubmed/35602216 http://dx.doi.org/10.1038/s43856-021-00036-w Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Plontke, Stefan K.
Rahne, Torsten
Curthoys, Ian S.
Håkansson, Bo
Fröhlich, Laura
A case series shows independent vestibular labyrinthine function after major surgical trauma to the human cochlea
title A case series shows independent vestibular labyrinthine function after major surgical trauma to the human cochlea
title_full A case series shows independent vestibular labyrinthine function after major surgical trauma to the human cochlea
title_fullStr A case series shows independent vestibular labyrinthine function after major surgical trauma to the human cochlea
title_full_unstemmed A case series shows independent vestibular labyrinthine function after major surgical trauma to the human cochlea
title_short A case series shows independent vestibular labyrinthine function after major surgical trauma to the human cochlea
title_sort case series shows independent vestibular labyrinthine function after major surgical trauma to the human cochlea
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9053204/
https://www.ncbi.nlm.nih.gov/pubmed/35602216
http://dx.doi.org/10.1038/s43856-021-00036-w
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