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Concise asymmetric synthesis of two natural oxacyclododecindione-type macrolactones from industrial waste

(S)-5-Methyl-tetrahydropyran-2-one 1 is a by-product in the production of key intermediates of steroidal hormones. Asymmetric synthesis of natural oxacyclododecindione-type macrolactones 2 and 3 has been realized for the first time from (S)-1 in seven and eight steps with 37% and 27% overall yield,...

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Detalles Bibliográficos
Autores principales:	Liu, Xian, Nie, Huifang, Yao, Lin, Jiang, Ru, Chen, Weiping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2020
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9053229/ https://www.ncbi.nlm.nih.gov/pubmed/35496927 http://dx.doi.org/10.1039/d0ra02994g

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