Unhelpful microbes inactivate diabetes drug

Drugs can modify the microbiome and, reciprocally, the microbiome can impact drug efficacy. A recent study in Nature identifies a potential mechanism through which oral and gut bacteria selectively inhibit the antidiabetic drug acarbose.

Detalles Bibliográficos
Autor principal: Abbott, Ben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Research Highlight
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9053282/
https://www.ncbi.nlm.nih.gov/pubmed/35603275
http://dx.doi.org/10.1038/s43856-021-00068-2
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author Abbott, Ben
author_facet Abbott, Ben
author_sort Abbott, Ben
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description Drugs can modify the microbiome and, reciprocally, the microbiome can impact drug efficacy. A recent study in Nature identifies a potential mechanism through which oral and gut bacteria selectively inhibit the antidiabetic drug acarbose.
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spelling pubmed-90532822022-05-20 Unhelpful microbes inactivate diabetes drug Abbott, Ben Commun Med (Lond) Research Highlight Drugs can modify the microbiome and, reciprocally, the microbiome can impact drug efficacy. A recent study in Nature identifies a potential mechanism through which oral and gut bacteria selectively inhibit the antidiabetic drug acarbose. Nature Publishing Group UK 2022-01-06 /pmc/articles/PMC9053282/ /pubmed/35603275 http://dx.doi.org/10.1038/s43856-021-00068-2 Text en © Springer Nature Limited 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Research Highlight
Abbott, Ben
Unhelpful microbes inactivate diabetes drug
title Unhelpful microbes inactivate diabetes drug
title_full Unhelpful microbes inactivate diabetes drug
title_fullStr Unhelpful microbes inactivate diabetes drug
title_full_unstemmed Unhelpful microbes inactivate diabetes drug
title_short Unhelpful microbes inactivate diabetes drug
title_sort unhelpful microbes inactivate diabetes drug
topic Research Highlight
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9053282/
https://www.ncbi.nlm.nih.gov/pubmed/35603275
http://dx.doi.org/10.1038/s43856-021-00068-2
work_keys_str_mv AT abbottben unhelpfulmicrobesinactivatediabetesdrug

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