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Advances in Hydrogen/Deuterium Exchange Mass Spectrometry and the Pursuit of Challenging Biological Systems

[Image: see text] Solution-phase hydrogen/deuterium exchange (HDX) coupled to mass spectrometry (MS) is a widespread tool for structural analysis across academia and the biopharmaceutical industry. By monitoring the exchangeability of backbone amide protons, HDX-MS can reveal information about highe...

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Detalles Bibliográficos
Autores principales:	James, Ellie I., Murphree, Taylor A., Vorauer, Clint, Engen, John R., Guttman, Miklos
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2021
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9053315/ https://www.ncbi.nlm.nih.gov/pubmed/34493042 http://dx.doi.org/10.1021/acs.chemrev.1c00279

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