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Dosimetric Analysis of Axillary Lymph Node Coverage Using High Tangents in the Prone Position for Left-Sided Breast Cancers

Aim/Objective: Prone positioning is often used to reduce the dose to organs at risk during adjuvant breast irradiation. High tangents are used with supine treatments in patients with the low-volume nodal disease to increase nodal coverage while minimizing toxicities. Our study aims to evaluate nodal...

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Autores principales: Malouff, Timothy D, Vallow, Laura A, Magalhaes, Wilza L, Seneviratne, Danushka S, Waddle, Mark R, Tzou, Katherine S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9053363/
https://www.ncbi.nlm.nih.gov/pubmed/35505718
http://dx.doi.org/10.7759/cureus.23613
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author Malouff, Timothy D
Vallow, Laura A
Magalhaes, Wilza L
Seneviratne, Danushka S
Waddle, Mark R
Tzou, Katherine S
author_facet Malouff, Timothy D
Vallow, Laura A
Magalhaes, Wilza L
Seneviratne, Danushka S
Waddle, Mark R
Tzou, Katherine S
author_sort Malouff, Timothy D
collection PubMed
description Aim/Objective: Prone positioning is often used to reduce the dose to organs at risk during adjuvant breast irradiation. High tangents are used with supine treatments in patients with the low-volume nodal disease to increase nodal coverage while minimizing toxicities. Our study aims to evaluate nodal coverage for patients treated in the prone position with high tangents. Materials and Methods: Our study analyzed the plans for 20 patients with early-stage, left-sided breast cancers treated at our institution from 2018 to 2019. All patients were treated in the prone position. Axillary nodal levels I-III were contoured, and treatment plans were generated using high tangents. The heart, bilateral lungs, and breast tissue were retrospectively contoured. All plans were evaluated to a dose of 42.4 Gy in 16 fractions. Results: Level I lymph node levels had a mean coverage of 99% of the prescription dose (range: 98-100%). Similarly, level II coverage was approximately 88% (range: 65-100%). The mean coverage for level III was approximately 25% (range: 0-52%). The mean heart dose, mean lung volume receiving ≥20 Gy (V20) for the bilateral lungs, and ipsilateral V20 were 1.69 Gy, 1.64%, and 3.56%, respectively. Conclusion:Treating patients in the prone position with high tangents provides excellent coverage of axillary levels I and II, although there is minimal coverage of axillary level III. Prospective trials are needed to evaluate the clinical outcomes when treating patients with high tangents in the prone position.
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spelling pubmed-90533632022-05-02 Dosimetric Analysis of Axillary Lymph Node Coverage Using High Tangents in the Prone Position for Left-Sided Breast Cancers Malouff, Timothy D Vallow, Laura A Magalhaes, Wilza L Seneviratne, Danushka S Waddle, Mark R Tzou, Katherine S Cureus Radiation Oncology Aim/Objective: Prone positioning is often used to reduce the dose to organs at risk during adjuvant breast irradiation. High tangents are used with supine treatments in patients with the low-volume nodal disease to increase nodal coverage while minimizing toxicities. Our study aims to evaluate nodal coverage for patients treated in the prone position with high tangents. Materials and Methods: Our study analyzed the plans for 20 patients with early-stage, left-sided breast cancers treated at our institution from 2018 to 2019. All patients were treated in the prone position. Axillary nodal levels I-III were contoured, and treatment plans were generated using high tangents. The heart, bilateral lungs, and breast tissue were retrospectively contoured. All plans were evaluated to a dose of 42.4 Gy in 16 fractions. Results: Level I lymph node levels had a mean coverage of 99% of the prescription dose (range: 98-100%). Similarly, level II coverage was approximately 88% (range: 65-100%). The mean coverage for level III was approximately 25% (range: 0-52%). The mean heart dose, mean lung volume receiving ≥20 Gy (V20) for the bilateral lungs, and ipsilateral V20 were 1.69 Gy, 1.64%, and 3.56%, respectively. Conclusion:Treating patients in the prone position with high tangents provides excellent coverage of axillary levels I and II, although there is minimal coverage of axillary level III. Prospective trials are needed to evaluate the clinical outcomes when treating patients with high tangents in the prone position. Cureus 2022-03-29 /pmc/articles/PMC9053363/ /pubmed/35505718 http://dx.doi.org/10.7759/cureus.23613 Text en Copyright © 2022, Malouff et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Radiation Oncology
Malouff, Timothy D
Vallow, Laura A
Magalhaes, Wilza L
Seneviratne, Danushka S
Waddle, Mark R
Tzou, Katherine S
Dosimetric Analysis of Axillary Lymph Node Coverage Using High Tangents in the Prone Position for Left-Sided Breast Cancers
title Dosimetric Analysis of Axillary Lymph Node Coverage Using High Tangents in the Prone Position for Left-Sided Breast Cancers
title_full Dosimetric Analysis of Axillary Lymph Node Coverage Using High Tangents in the Prone Position for Left-Sided Breast Cancers
title_fullStr Dosimetric Analysis of Axillary Lymph Node Coverage Using High Tangents in the Prone Position for Left-Sided Breast Cancers
title_full_unstemmed Dosimetric Analysis of Axillary Lymph Node Coverage Using High Tangents in the Prone Position for Left-Sided Breast Cancers
title_short Dosimetric Analysis of Axillary Lymph Node Coverage Using High Tangents in the Prone Position for Left-Sided Breast Cancers
title_sort dosimetric analysis of axillary lymph node coverage using high tangents in the prone position for left-sided breast cancers
topic Radiation Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9053363/
https://www.ncbi.nlm.nih.gov/pubmed/35505718
http://dx.doi.org/10.7759/cureus.23613
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