Extensive Colonic Pneumatosis, Pneumoperitoneum, Pneumomediastinum and Subcutaneous Emphysema – a Rare Pattern of Complications in Acute Lymphoblastic Leukemia

Teaching Point: Intestinal pneumatosis associated with pneumoperitoneum, pneumomediastinum, and subcutaneous emphysema is an extremely rare complication of leukemia; even though its imaging appearance can be alarming, a benign treatment-associated etiology should always be considered in this subset of patients so that unnecessary interventions can be avoided.