Mass spectrometric analysis of acid-assisted photochemical release of the trimethyl lock system on the monolayers on gold

We report the acid-assisted photolysis of the trimethyl lock system which has long been harnessed for a variety of applications such as drug delivery, cellular imaging, enzyme activity assays, and surface patterning. By mass spectrometric analysis, we found that photoinduced intramolecular cyclizati...

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Detalles Bibliográficos
Autores principales: Yu, Geunhyeok, Yeo, Woon-Seok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9053594/
https://www.ncbi.nlm.nih.gov/pubmed/35515585
http://dx.doi.org/10.1039/d0ra02110e
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author Yu, Geunhyeok
Yeo, Woon-Seok
author_facet Yu, Geunhyeok
Yeo, Woon-Seok
author_sort Yu, Geunhyeok
collection PubMed
description We report the acid-assisted photolysis of the trimethyl lock system which has long been harnessed for a variety of applications such as drug delivery, cellular imaging, enzyme activity assays, and surface patterning. By mass spectrometric analysis, we found that photoinduced intramolecular cyclization and the ensuing release of the pendant groups of the trimethyl lock on the self-assembled monolayers proceeded cleanly in the presence of HCl, to give a high yield.
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spelling pubmed-90535942022-05-04 Mass spectrometric analysis of acid-assisted photochemical release of the trimethyl lock system on the monolayers on gold Yu, Geunhyeok Yeo, Woon-Seok RSC Adv Chemistry We report the acid-assisted photolysis of the trimethyl lock system which has long been harnessed for a variety of applications such as drug delivery, cellular imaging, enzyme activity assays, and surface patterning. By mass spectrometric analysis, we found that photoinduced intramolecular cyclization and the ensuing release of the pendant groups of the trimethyl lock on the self-assembled monolayers proceeded cleanly in the presence of HCl, to give a high yield. The Royal Society of Chemistry 2020-05-11 /pmc/articles/PMC9053594/ /pubmed/35515585 http://dx.doi.org/10.1039/d0ra02110e Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/
spellingShingle Chemistry
Yu, Geunhyeok
Yeo, Woon-Seok
Mass spectrometric analysis of acid-assisted photochemical release of the trimethyl lock system on the monolayers on gold
title Mass spectrometric analysis of acid-assisted photochemical release of the trimethyl lock system on the monolayers on gold
title_full Mass spectrometric analysis of acid-assisted photochemical release of the trimethyl lock system on the monolayers on gold
title_fullStr Mass spectrometric analysis of acid-assisted photochemical release of the trimethyl lock system on the monolayers on gold
title_full_unstemmed Mass spectrometric analysis of acid-assisted photochemical release of the trimethyl lock system on the monolayers on gold
title_short Mass spectrometric analysis of acid-assisted photochemical release of the trimethyl lock system on the monolayers on gold
title_sort mass spectrometric analysis of acid-assisted photochemical release of the trimethyl lock system on the monolayers on gold
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9053594/
https://www.ncbi.nlm.nih.gov/pubmed/35515585
http://dx.doi.org/10.1039/d0ra02110e
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