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In vivo and in vitro evaluation of dihydroartemisinin prodrug nanocomplexes as a nano-drug delivery system: characterization, pharmacokinetics and pharmacodynamics

To develop new, more effective and lower toxicity antitumor dihydroartemisinin (DHA) nanocomplexes, a DHA prodrug synthesized in this study was used to prepare DHA prodrug self-assembled nanocomplexes (DHANPs) by molecular self-assembly technology. The optimization, pharmacokinetics and in vitro and...

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Detalles Bibliográficos
Autores principales:	Ren, Guolian, Chen, Pei, Tang, Jiaqi, Guo, Wenju, Wang, Rongrong, Li, Ning, Li, Yujie, Zhang, Guoshun, Wang, Ruili, Zhang, Shuqiu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2020
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9053626/ https://www.ncbi.nlm.nih.gov/pubmed/35521441 http://dx.doi.org/10.1039/d0ra02150d

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