Schizophrenia Risk Mediated by microRNA Target Genes Overlapped by Genome-Wide Rare Copy Number Variation in 22q11.2 Deletion Syndrome

The 22q11.2 deletion is associated with >20-fold increased risk for schizophrenia. The presence of gene DGCR8 in the 22q11.2 deletion region has suggested microRNA (miRNA) dysregulation as possibly contributing to this risk. We therefore investigated the role of miRNA target genes in the context...

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Detalles Bibliográficos
Autores principales: Ying, Shengjie, Heung, Tracy, Zhang, Zhaolei, Yuen, Ryan K. C., Bassett, Anne S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9053669/
https://www.ncbi.nlm.nih.gov/pubmed/35495153
http://dx.doi.org/10.3389/fgene.2022.812183

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