Reengineering the programming of a functional domain of an iterative highly reducing polyketide synthase

A structural model of the enoyl reductase (ER) catalytic domain of the fungal highly-reducing polyketide synthase squalestatin tetraketide synthase (SQTKS) was developed. Simulated docking of substrates and inhibitors allowed the definition of active site residues involved in catalysis and substrate...

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Detalles Bibliográficos
Autores principales: Piech, Oliver, Cox, Russell J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9053739/
https://www.ncbi.nlm.nih.gov/pubmed/35517211
http://dx.doi.org/10.1039/d0ra04026f

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9053739/
https://www.ncbi.nlm.nih.gov/pubmed/35517211
http://dx.doi.org/10.1039/d0ra04026f

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