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Therapeutic efficacy of humanized monoclonal antibodies targeting dengue virus nonstructural protein 1 in the mouse model

Dengue virus (DENV) which infects about 390 million people per year in tropical and subtropical areas manifests various disease symptoms, ranging from fever to life-threatening hemorrhage and even shock. To date, there is still no effective treatment for DENV disease, but only supportive care. DENV...

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Detalles Bibliográficos
Autores principales: Tien, Sen-Mao, Chang, Po-Chun, Lai, Yen-Chung, Chuang, Yung-Chun, Tseng, Chin-Kai, Kao, Yu-San, Huang, Hong-Jyun, Hsiao, Yu-Peng, Liu, Yi-Ling, Lin, Hsing-Han, Chu, Chien-Chou, Cheng, Miao-Huei, Ho, Tzong-Shiann, Chang, Chih-Peng, Ko, Shu-Fen, Shen, Che-Piao, Anderson, Robert, Lin, Yee-Shin, Wan, Shu-Wen, Yeh, Trai-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9053773/
https://www.ncbi.nlm.nih.gov/pubmed/35486576
http://dx.doi.org/10.1371/journal.ppat.1010469