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Comprehensive transcriptome profiling of BET inhibitor-treated HepG2 cells

Hepatocellular carcinoma (HCC) is the most common primary liver cancer and poor prognosis. Emerging evidence suggests that epigenetic alterations play a crucial role in HCC, suggesting epigenetic inhibition as a promising therapeutic approach. Indeed, the bromodomain and extra-terminal (BET) inhibit...

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Detalles Bibliográficos
Autores principales: Baek, Mina, Chai, Jin Choul, Choi, Hae In, Yoo, Eunyoung, Binas, Bert, Lee, Young Seek, Jung, Kyoung Hwa, Chai, Young Gyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9053788/
https://www.ncbi.nlm.nih.gov/pubmed/35486664
http://dx.doi.org/10.1371/journal.pone.0266966