Cargando…

Comprehensive transcriptome profiling of BET inhibitor-treated HepG2 cells

Hepatocellular carcinoma (HCC) is the most common primary liver cancer and poor prognosis. Emerging evidence suggests that epigenetic alterations play a crucial role in HCC, suggesting epigenetic inhibition as a promising therapeutic approach. Indeed, the bromodomain and extra-terminal (BET) inhibit...

Descripción completa

Detalles Bibliográficos
Autores principales:	Baek, Mina, Chai, Jin Choul, Choi, Hae In, Yoo, Eunyoung, Binas, Bert, Lee, Young Seek, Jung, Kyoung Hwa, Chai, Young Gyu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9053788/ https://www.ncbi.nlm.nih.gov/pubmed/35486664 http://dx.doi.org/10.1371/journal.pone.0266966

Ejemplares similares

BET inhibitor suppresses migration of human hepatocellular carcinoma by inhibiting SMARCA4
por: Choi, Hae In, et al.
Publicado: (2021)

Analysis of differentially expressed long non-coding RNAs in LPS-induced human HMC3 microglial cells
por: Baek, Mina, et al.
Publicado: (2022)

The BET inhibitor attenuates the inflammatory response and cell migration in human microglial HMC3 cell line
por: Baek, Mina, et al.
Publicado: (2021)

Targeting of non-coding RNAs encoded by novel MYC enhancers inhibits the proliferation of human hepatic carcinoma cells in vitro
por: Choi, Hae In, et al.
Publicado: (2022)

The bromodomain inhibitor JQ1 up-regulates the long non-coding RNA MALAT1 in cultured human hepatic carcinoma cells
por: Choi, Hae In, et al.
Publicado: (2022)

Transcriptome sequencing wide functional analysis of human mesenchymal stem cells in response to TLR4 ligand
por: Kim, Sun Hwa, et al.
Publicado: (2016)

Dual transcriptome sequencing reveals resistance of TLR4 ligand-activated bone marrow-derived macrophages to inflammation mediated by the BET inhibitor JQ1
por: Das, Amitabh, et al.
Publicado: (2015)

RNA sequencing reveals distinct mechanisms underlying BET inhibitor JQ1-mediated modulation of the LPS-induced activation of BV-2 microglial cells
por: Jung, Kyoung Hwa, et al.
Publicado: (2015)

Transcriptome sequencing of microglial cells stimulated with TLR3 and TLR4 ligands
por: Das, Amitabh, et al.
Publicado: (2015)

Dual RNA Sequencing Reveals the Expression of Unique Transcriptomic Signatures in Lipopolysaccharide-Induced BV-2 Microglial Cells
por: Das, Amitabh, et al.
Publicado: (2015)

GSK-J4-Mediated Transcriptomic Alterations in Differentiating Embryoid Bodies
por: Mandal, Chanchal, et al.
Publicado: (2017)

Transcriptome sequencing reveals that LPS-triggered transcriptional responses in established microglia BV2 cell lines are poorly representative of primary microglia
por: Das, Amitabh, et al.
Publicado: (2016)

Transcriptomic Profiling and H3K27me3 Distribution Reveal Both Demethylase-Dependent and Independent Regulation of Developmental Gene Transcription in Cell Differentiation
por: Kang, Sung Chul, et al.
Publicado: (2015)

Epigenetic regulation of IFITM1 expression in lipopolysaccharide-stimulated human mesenchymal stromal cells
por: Kim, Sun Hwa, et al.
Publicado: (2020)

RNA Sequencing Reveals the Alteration of the Expression of Novel Genes in Ethanol-Treated Embryoid Bodies
por: Mandal, Chanchal, et al.
Publicado: (2016)

RNA sequencing reveals resistance of TLR4 ligand-activated microglial cells to inflammation mediated by the selective jumonji H3K27 demethylase inhibitor
por: Das, Amitabh, et al.
Publicado: (2017)

A proteomic analysis of mushroom polysaccharide-treated HepG2 cells
por: Chai, Yangyang, et al.
Publicado: (2016)

Genome-scale DNA methylation pattern profiling of human bone marrow mesenchymal stem cells in long-term culture
por: Choi, Mi Ran, et al.
Publicado: (2012)

Energy Metabolism in Mycobacterium gilvum PYR-GCK: Insights from Transcript Expression Analyses Following Two States of Induction
por: Badejo, Abimbola Comfort, et al.
Publicado: (2014)

TLR3-/4-Priming Differentially Promotes Ca(2+) Signaling and Cytokine Expression and Ca(2+)-Dependently Augments Cytokine Release in hMSCs
por: Park, Kyoung Sun, et al.
Publicado: (2016)

High-Resolution Mapping and Dynamics of the Transcriptome, Transcription Factors, and Transcription Co-Factor Networks in Classically and Alternatively Activated Macrophages
por: Das, Amitabh, et al.
Publicado: (2018)

Genetic populations of Bacillus anthracis isolates from Korea
por: Jung, Kyoung Hwa, et al.
Publicado: (2012)

Natural Thiols, but Not Thioethers, Attenuate Patulin-Induced Endoplasmic Reticulum Stress in HepG2 Cells
por: Kim, Hye Mi, et al.
Publicado: (2021)

iTRAQ-Based Quantitative Proteomic Analysis of the Inhibitory Effects of Polysaccharides from Viscum coloratum (Kom.) Nakai on HepG2 Cells
por: Chai, Yangyang, et al.
Publicado: (2017)

Involvement of Endoplasmic Reticulum Stress in Palmitate-induced Apoptosis in HepG2 Cells
por: Cho, Hyang-Ki, et al.
Publicado: (2008)

Artificial cells eavesdropping on HepG2 cells
por: Westensee, Isabella Nymann, et al.
Publicado: (2023)

Effects of Elaidic Acid on Lipid Metabolism in HepG2 Cells, Investigated by an Integrated Approach of Lipidomics, Transcriptomics and Proteomics
por: Vendel Nielsen, Lone, et al.
Publicado: (2013)

Induction of Heme Oxygenase-1 Inhibits Cell Death in Crotonaldehyde-Stimulated HepG2 Cells via the PKC-δ -p38 -Nrf2 Pathway
por: Lee, Seung Eun, et al.
Publicado: (2012)

Anti-tumor effect of volatile oil from Houttuynia cordata Thunb. on HepG2 cells and HepG2 tumor-bearing mice
por: Yang, Linsong, et al.
Publicado: (2019)

DNMT1/PKR double knockdowned HepG2 (HepG2-DP) cells have high hepatic function and differentiation ability
por: Tanaka-yachi, Rieko, et al.
Publicado: (2022)

Hepatoprotective Effect of Gallotannin-enriched Extract Isolated from Gall on Hydrogen Peroxide-induced Cytotoxicity in HepG2 Cells
por: Go, Jun, et al.
Publicado: (2017)

Taurine reduces the secretion of apolipoprotein B100 and lipids in HepG2 cells
por: Yanagita, Teruyoshi, et al.
Publicado: (2008)

Comparison of Transcriptomics Changes Induced by TCS and MTCS Exposure in Human Hepatoma HepG2 Cells
por: Li, Xiaoqian, et al.
Publicado: (2020)

Transcriptome Analyses of the Anti-Proliferative Effects of 20(S)-Ginsenoside Rh2 on HepG2 Cells
por: Zhang, Ji, et al.
Publicado: (2019)

Characterization of dengue virus entry into HepG2 cells
por: Suksanpaisan, Lukkana, et al.
Publicado: (2009)

Selectivity of biopolymer membranes using HepG2 cells
por: Lü, Dongyuan, et al.
Publicado: (2015)

Curcumin Effect on Copper Transport in HepG2 Cells
por: Berzina, Anita, et al.
Publicado: (2018)

Cholesterol-lowing effect of taurine in HepG2 cell
por: Guo, Junxia, et al.
Publicado: (2017)

Nevirapine induced mitochondrial dysfunction in HepG2 cells
por: Paemanee, Atchara, et al.
Publicado: (2017)

The Expectation and Reality of the HepG2 Core Metabolic Profile
por: Kiseleva, Olga I., et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_9el8hk98m10h4g3cvtb1493bvp