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FCHO controls AP2’s initiating role in endocytosis through a PtdIns(4,5)P(2)-dependent switch

Clathrin-mediated endocytosis (CME) is the main mechanism by which mammalian cells control their cell surface proteome. Proper operation of the pivotal CME cargo adaptor AP2 requires membrane-localized Fer/Cip4 homology domain-only proteins (FCHO). Here, live-cell enhanced total internal reflection...

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Detalles Bibliográficos
Autores principales:	Zaccai, Nathan R., Kadlecova, Zuzana, Dickson, Veronica Kane, Korobchevskaya, Kseniya, Kamenicky, Jan, Kovtun, Oleksiy, Umasankar, Perunthottathu K., Wrobel, Antoni G., Kaufman, Jonathan G. G., Gray, Sally R., Qu, Kun, Evans, Philip R., Fritzsche, Marco, Sroubek, Filip, Höning, Stefan, Briggs, John A. G., Kelly, Bernard T., Owen, David J., Traub, Linton M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2022
Materias:	Biomedicine and Life Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9054013/ https://www.ncbi.nlm.nih.gov/pubmed/35486718 http://dx.doi.org/10.1126/sciadv.abn2018

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