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Selective clonal persistence of human retroviruses in vivo: Radial chromatin organization, integration site, and host transcription

The human retroviruses HTLV-1 (human T cell leukemia virus type 1) and HIV-1 persist in vivo as a reservoir of latently infected T cell clones. It is poorly understood what determines which clones survive in the reservoir. We compared >160,000 HTLV-1 integration sites (>40,000 HIV-1 sites) fro...

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Detalles Bibliográficos
Autores principales:	Melamed, Anat, Fitzgerald, Tomas W., Wang, Yuchuan, Ma, Jian, Birney, Ewan, Bangham, Charles R. M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2022
Materias:	Biomedicine and Life Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9054021/ https://www.ncbi.nlm.nih.gov/pubmed/35486737 http://dx.doi.org/10.1126/sciadv.abm6210

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