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SARS-CoV-2 Nsp14 mediates the effects of viral infection on the host cell transcriptome

Viral infection involves complex set of events orchestrated by multiple viral proteins. To identify functions of SARS-CoV-2 proteins, we performed transcriptomic analyses of cells expressing individual viral proteins. Expression of Nsp14, a protein involved in viral RNA replication, provoked a drama...

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Detalles Bibliográficos
Autores principales: Zaffagni, Michela, Harris, Jenna M, Patop, Ines L, Pamudurti, Nagarjuna Reddy, Nguyen, Sinead, Kadener, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9054133/
https://www.ncbi.nlm.nih.gov/pubmed/35293857
http://dx.doi.org/10.7554/eLife.71945