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A glass nanopore ionic sensor for surface charge analysis
Surface charge-based nanopore characterization techniques unfold unique properties and provide a powerful platform for a variety of sensing applications. In this paper, we have proposed a nanoconfined inner wall surface charge characterization method with glass nanopores. The glass nanopores were fu...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9054376/ https://www.ncbi.nlm.nih.gov/pubmed/35518750 http://dx.doi.org/10.1039/d0ra03353g |
Sumario: | Surface charge-based nanopore characterization techniques unfold unique properties and provide a powerful platform for a variety of sensing applications. In this paper, we have proposed a nanoconfined inner wall surface charge characterization method with glass nanopores. The glass nanopores were functionalized with DNA aptamers that were designed for mercury (Hg(2+)) ion immobilization by forming thymine–Hg(2+)–thymine structures. The surface charge of the nanopores was modulated by surface chemistry and Hg(2+) ion concentrations and analysed by combining zeta potential measurements on glass slides and the ionic current rectification ratio of the nanopores. Also, 1 pM Hg(2+) ions could be detected by the nanopores. |
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