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A glass nanopore ionic sensor for surface charge analysis

Surface charge-based nanopore characterization techniques unfold unique properties and provide a powerful platform for a variety of sensing applications. In this paper, we have proposed a nanoconfined inner wall surface charge characterization method with glass nanopores. The glass nanopores were fu...

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Detalles Bibliográficos
Autores principales: Chen, Songyue, Chen, Hong, Zhang, Jian, Dong, Hepeng, Zhan, Kan, Tang, Yongliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9054376/
https://www.ncbi.nlm.nih.gov/pubmed/35518750
http://dx.doi.org/10.1039/d0ra03353g
Descripción
Sumario:Surface charge-based nanopore characterization techniques unfold unique properties and provide a powerful platform for a variety of sensing applications. In this paper, we have proposed a nanoconfined inner wall surface charge characterization method with glass nanopores. The glass nanopores were functionalized with DNA aptamers that were designed for mercury (Hg(2+)) ion immobilization by forming thymine–Hg(2+)–thymine structures. The surface charge of the nanopores was modulated by surface chemistry and Hg(2+) ion concentrations and analysed by combining zeta potential measurements on glass slides and the ionic current rectification ratio of the nanopores. Also, 1 pM Hg(2+) ions could be detected by the nanopores.