Cargando…
BCKDK Promotes Ovarian Cancer Proliferation and Migration by Activating the MEK/ERK Signaling Pathway
BACKGROUND: Ovarian cancer (OC) is the most fatal gynecologic cancer. The branched-chain α-keto acid dehydrogenase kinase (BCKDK) plays an important role in many serious human diseases, including cancers. Its function in promoting cell proliferation and migration has been reported in various cancers...
Autores principales: | Li, Huashun, Yu, Dongyang, Li, Lianbing, Xiao, Juanjuan, Zhu, Yijian, Liu, Yi, Mou, Li, Tian, Yafei, Chen, Linbo, Zhu, Feng, Duan, Qiuhong, Xue, Peipei |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9054484/ https://www.ncbi.nlm.nih.gov/pubmed/35498541 http://dx.doi.org/10.1155/2022/3691635 |
Ejemplares similares
-
Phosphorylation of BCKDK of BCAA catabolism at Y246 by Src promotes metastasis of colorectal cancer
por: Tian, Qin, et al.
Publicado: (2020) -
BCKDK of BCAA Catabolism Cross-talking With the MAPK Pathway Promotes Tumorigenesis of Colorectal Cancer
por: Xue, Peipei, et al.
Publicado: (2017) -
APN-mediated phosphorylation of BCKDK promotes hepatocellular carcinoma metastasis and proliferation via the ERK signaling pathway
por: Zhai, Mengying, et al.
Publicado: (2020) -
Down-regulation of TRIB3 inhibits the progression of ovarian cancer via MEK/ERK signaling pathway
por: Wang, Shuang, et al.
Publicado: (2020) -
BCKDK alters the metabolism of non-small cell lung cancer
por: Wang, Yanhui, et al.
Publicado: (2021)