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Inhibitory effects of UDP-glucuronosyltransferase (UGT) typical ligands against E. coli beta-glucuronidase (GUS)

UDP-glucuronosyltransferases (UGTs) and β-glucuronidase (GUS) catalyze entirely distinct metabolism reactions. UGTs are responsible for the glucuronidation of a variety of drugs, endogenous and environmental chemicals, whereas GUS hydrolyzes glucuronides and liberates the parent substrates. Informat...

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Detalles Bibliográficos
Autores principales:	Xiao, Ling, Chi, Dehui, Sheng, Guiju, Li, Wenjuan, Lin, Penghui, Liang, Sicheng, Zhu, Liangliang, Dong, Peipei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2020
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9054634/ https://www.ncbi.nlm.nih.gov/pubmed/35520305 http://dx.doi.org/10.1039/d0ra02311f

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