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A novel artificial intelligence protocol to investigate potential leads for Parkinson's disease

Previous studies have shown that small molecule inhibitors of NLRP3 may be a potential treatment for Parkinson's disease (PD). NACHT, LRR and PYD domains-containing protein 3 (NLRP3), heat shock protein HSP 90-beta (HSP90AB1), caspase-1 (CASP1) and cellular tumor antigen p53 (TP53) have signifi...

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Detalles Bibliográficos
Autores principales: Chen, Zhi-Dong, Zhao, Lu, Chen, Hsin-Yi, Gong, Jia-Ning, Chen, Xu, Chen, Calvin Yu-Chian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9054719/
https://www.ncbi.nlm.nih.gov/pubmed/35520357
http://dx.doi.org/10.1039/d0ra04028b