In-situ scalable manufacturing of Epstein–Barr virus-specific T-cells using bioreactor with an expandable culture area (BECA)

The ex-vivo expansion of antigen-specific T-cells for adoptive T-cell immunotherapy requires active interaction between T-cells and antigen-presenting cells therefore culture density and environment become important variables to control. Maintenance of culture density in a static environment is trad...

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Detalles Bibliográficos
Autores principales: Chen, Sixun, Bin Abdul Rahim, Ahmad Amirul, Wang, Who-Whong, Cheong, Rachael, Prabhu, Akshaya V., Tan, Jerome Zu Yao, Naing, May Win, Toh, Han Chong, Liu, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9054749/
https://www.ncbi.nlm.nih.gov/pubmed/35487951
http://dx.doi.org/10.1038/s41598-022-11015-z

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