Regulation of chromatin accessibility by the histone chaperone CAF-1 sustains lineage fidelity

Cell fate commitment is driven by dynamic changes in chromatin architecture and activity of lineage-specific transcription factors (TFs). The chromatin assembly factor-1 (CAF-1) is a histone chaperone that regulates chromatin architecture by facilitating nucleosome assembly during DNA replication. A...

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Detalles Bibliográficos
Autores principales: Franklin, Reuben, Guo, Yiming, He, Shiyang, Chen, Meijuan, Ji, Fei, Zhou, Xinyue, Frankhouser, David, Do, Brian T., Chiem, Carmen, Jang, Mihyun, Blanco, M. Andres, Vander Heiden, Matthew G., Rockne, Russell C., Ninova, Maria, Sykes, David B., Hochedlinger, Konrad, Lu, Rui, Sadreyev, Ruslan I., Murn, Jernej, Volk, Andrew, Cheloufi, Sihem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9054786/
https://www.ncbi.nlm.nih.gov/pubmed/35487911
http://dx.doi.org/10.1038/s41467-022-29730-6

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