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Proton pump inhibitors reduce the survival of advanced lung cancer patients with therapy of gefitinib or erlotinib

Gefitinib and erlotinib are the first-line tyrosine kinase inhibitors (TKI) for advanced non-small-cell lung cancer. However, co-administration of either drug with proton pump inhibitors (PPI) or histamine-2 receptor antagonists (H2RA) may reduce TKI’s bioavailability. Therefore, we aimed to investi...

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Detalles Bibliográficos
Autores principales:	Lee, Chia-Han, Shen, Mei-Chiou, Tsai, Ming-Ju, Chang, Jung-San, Huang, Yaw-Bin, Yang, Yi-Hsin, Hsieh, Kun-Pin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9054789/ https://www.ncbi.nlm.nih.gov/pubmed/35488047 http://dx.doi.org/10.1038/s41598-022-10938-x

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