Neuron-specific enolase promotes stem cell-like characteristics of small-cell lung cancer by downregulating NBL1 and activating the BMP2/Smad/ID1 pathway

Little is known about the biological functions of neuron-specific enolase (NSE) as a specific biomarker for small-cell lung cancer (SCLC). Herein, we elucidate the effect and mechanism of NSE on SCLC stem cell-like characteristics. Upregulated NSE expression was observed in spheroid cells. The gain-...

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Detalles Bibliográficos
Autores principales: Lu, Lin, Zha, Zhiqiang, Zhang, Peiling, Wang, Peipei, Liu, Xia, Fang, Xisheng, Weng, Chengyin, Li, Baoxiu, Mao, Haibo, Wang, Lina, Guan, Mingmei, Wu, Yong, Xu, Zhixiang, Liu, Zhongqiu, Liu, Guolong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9054797/
https://www.ncbi.nlm.nih.gov/pubmed/35487890
http://dx.doi.org/10.1038/s41389-022-00396-5

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