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Arrhythmogenic influence of mutations in a myocyte-based computational model of the pulmonary vein sleeve

In the heart, electrophysiological dysregulation arises from defects at many biological levels (from point mutations in ion channel proteins to gross structural abnormalities). These defects disrupt the normal pattern of electrical activation, producing ectopic activity and reentrant arrhythmia. To...

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Detalles Bibliográficos
Autores principales: Jæger, Karoline Horgmo, Edwards, Andrew G., Giles, Wayne R., Tveito, Aslak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9054808/
https://www.ncbi.nlm.nih.gov/pubmed/35487957
http://dx.doi.org/10.1038/s41598-022-11110-1