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Molecular basis of antibiotic self-resistance in a bee larvae pathogen
Paenibacillus larvae, the causative agent of the devastating honey-bee disease American Foulbrood, produces the cationic polyketide-peptide hybrid paenilamicin that displays antibacterial and antifungal activity. Its biosynthetic gene cluster contains a gene coding for the N-acetyltransferase PamZ....
Autores principales: | Dang, Tam, Loll, Bernhard, Müller, Sebastian, Skobalj, Ranko, Ebeling, Julia, Bulatov, Timur, Gensel, Sebastian, Göbel, Josefine, Wahl, Markus C., Genersch, Elke, Mainz, Andi, Süssmuth, Roderich D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9054821/ https://www.ncbi.nlm.nih.gov/pubmed/35487884 http://dx.doi.org/10.1038/s41467-022-29829-w |
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