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In crystallo observation of three metal ion promoted DNA polymerase misincorporation
Error-free replication of DNA is essential for life. Despite the proofreading capability of several polymerases, intrinsic polymerase fidelity is in general much higher than what base-pairing energies can provide. Although researchers have investigated this long-standing question with kinetics, stru...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9054841/ https://www.ncbi.nlm.nih.gov/pubmed/35487947 http://dx.doi.org/10.1038/s41467-022-30005-3 |