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An effective AKT inhibitor-PARP inhibitor combination therapy for recurrent ovarian cancer

BACKGROUND: Although the use of PARP inhibitor has received considerable amount of attention in ovarian cancer, PARP inhibitor resistance still emerges with disease progression. PI3K/AKT pathway inhibitors have been proposed to synergize with PARP inhibition to slow tumor growth, but the exact molec...

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Detalles Bibliográficos
Autores principales:	Xu, Jing, Gao, Yi, Luan, Xiaotian, Li, Ke, Wang, Jing, Dai, Yilin, Kang, Mingyi, Lu, Chong, Zhang, Minhua, Lu, Chris X., Kang, Yu, Xu, Congjian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9054880/ https://www.ncbi.nlm.nih.gov/pubmed/35419627 http://dx.doi.org/10.1007/s00280-022-04403-9

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